Exact(6)
The remaining 4,146 comparisons were from differences in age, cell line, cell type, development stage, dose, genotype/variation, protocol, species, temperature, time, tissue and others, and are excluded from this study.
Even at the submission stage, dose justifications may still be necessary.
Subgroup analyses were carried out by sex, pubertal stage, dose of vitamin D, and baseline serum vitamin D concentration.
12 Depression was a better predictor than the commonly accepted risk factors for malnutrition: gender, age, presence of a live-in carer, tumour stage, dose of radiation, concurrent chemotherapy or surgery.
When heterogeneity was considered substantial, we explored its causes by carrying out prespecified subgroup analyses where data were available that is, subgroups by sex, pubertal stage, dose of vitamin D, baseline vitamin D levels, compliance, and adequacy of allocation concealment.
We performed a priori subgroup analyses by sex, pubertal stage, dose of vitamin D, and baseline vitamin D levels to determine whether the effects of supplementation varied by these factors.
Similar(54)
In the case of a nonmonotonic dose response curve where more doses are required to adequately explore the curve, substantial savings in sample size are achieved compared with a traditional strategy which offers only selection and promotion from among initial first stage doses.
It's another scene, in a way, a staged dose of something approaching reality, only not as interesting as what surrounds it and not as strange.
A Leerink Swann analyst, Joshua Schimmer, said in a research note that if late-stage dosing had been suspended, "we believe that this is the final blow for what was perceived as a compound in trouble after the disappointing data on hypersensitivity and nausea/vomiting presented at the American Diabetes Association this year".
Recently, MK-0974 has been tested in a randomized, double-blind, placebo-and active-controlled, outpatient study with a two-stage, dose-ranging design to test safety and effectiveness [69].
We conducted a two-stage dose-response random-effects meta-analysis to combine study-specific RRs (15).
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