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Induced deletion of NOTCH1, a transmembrane transcription activator, in mouse results in an early stage blockage in T-cell development [ 47].
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As the graph shows, the length of the vectors represents the velocity, which falls from 25%% blockage stage to 99%% blockage stage.
The velocity of fluid particles around the test model in the pipe varied considerably and increased from 25%% blockage stage to 99%% blockage stage, as shown in Fig. 5.
Although previous studies suggested glioma expression of oligodendrocyte progenitor cell antigen NG2 and PDGFRα, and transcription factor Olig1/2 [1]–[3], the lineage commitment and the stage of differentiation blockage of glioma cells are not clarified [4].
PRRSV infection of monocyte-derived dendritic cells (Mo-DC) induced the transcription of IFN- α/- β but no detectable IFN- α in culture supernatant, suggesting a blockage at posttranscriptional stage [ 45].
Another blockage point is in the courts.
However, it was re-expressed in secondary hair follicle germs in Ta mice in late stages [14], [15]; and complete blockage of Shh was seen when a Dkk4 transgene was expressed in Ta.
One possibility is suggested by work with P. berghei [19] where the blockage of liver-stage parasite development in BALB/c liver has been correlated with the immediate liver inflammatory response [27].
AML is characterized by genetic and epigenetic alterations in progenitor cells that produce complete or partial blockage at different stages of myeloid differentiation and uncontrolled proliferation.
In order to identify new stromal genes potentially involved in these mechanisms, we developed a systematic approach of gene expression profiling to evaluate, in comparison to the wild-type littermate, the gene expression of several thymus deficient mice showing a blockage at different stages of T cell development [ 2- 4].
In addition, the sodium flow from Fuel and storage sub-assemblies is also measured during commissioning stage in order to identify any blockage in the hydraulic paths of respective sub-assemblies.
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