Sentence examples for stage assay from inspiring English sources

A series of 2- 2-hydrazinyl thiazole derivatives with a wide range of substitutions at 2- 2-hydrazinyl thiazoleere synthesized, characterized and evaluated their inhibitory potentials against plasmodium falciparum, NF54, by in vitro blood stage assay.

This assay is typically an end stage assay after significant phage amplification (>10 PFU/mL) in a fermentation culture has been achieved.

The in vitro liver stage assay used for screening is an image-based assay with HepG2-A16-CD81EGFP cells infected with Plasmodium yoelii sporozoites.

However, further optimization of the P. cynomolgi liver stage assay and miniaturization to increase the throughput are required before screens of larger, more chemically diverse libraries can be achieved.

We evaluated the reproducibility of the P. cynomolgi in vitro liver stage assay and used it in a low-throughput screen of compounds with demonstrated antimalarial activity, identifying a new potent non-8-aminoquinoline compound that, similar to primaquine, efficiently kills the early developmental forms of all liver stages in vitro.

While these values differ due to residual variability in this early stage assay, each is well below the levels of viremia seen in many diseases and competitive with many established laboratory methods such as qPCR, ELISA, and microscopy, as well as POC lab-on-chip devices which range, in their respective limits of detection, from 10 10 virus particles/mL.

A plethora of new laboratory assays are being developed to interrogate malaria transmission from the gametocyte to the sporozoite stage: assays that augment well-established field protocols to determine the entomological inoculation rate.

This model potentially generates a three-stage assay that allows investigation of cells: i) contained by BM; ii) as they invade across BM; iii) as they invade more distally into surrounding collagen.

Samples were also analysed undiluted in a manual one-stage assay in which 0.1 mls of congenital FVIII deficient plasma (Technoclone Ltd ,Dorking, UK), and 0.1 mls of test plasma or media, were aliquoted into glass tubes, and a stop watch started immediately after the addition to the tubes of 0.1 mls of APTT reagent (Actin FS, Dade, Sysmex UK Ltd ,Milton Keynes, UK).

The recombinant molecules were first assessed for their clotting activity in a two-stage assay.

Certain nudix hydrolases were examined for endopolyphosphatase activity, typically in a two-stage assay.