Homeostatic plasticity allows developing circuits to function stably by maximizing their dynamic range as new inputs become incorporated (Bucher et al., 2005; Marder and Goaillard, 2006; Pratt and Aizenman, 2007).
After the initial inoculation, the anode biocatalyst did not require any replacement and functioned stably with nutrient replacement, substrate addition, pH control, and periodic flushing of the anode to remove planktonic cells, or excess microbial biomass over the complete 10-month period.
In the future, it would be interesting to see whether an HGF-GFP reporter cell line, stably expressing this shRNA, could function without tubulation.
In addition, they can be known from experiments that the manufacturing technology is advanced and feasible, and its high resilience and stably self-locked function can achieve instantaneously sensing.
This regulation is lost in cells (T47D) where we stably inhibited RARα function with either a RARα antagonist, or a dominant negative RARα mutant and in cells (MDA-MB-231) that lack endogenous RARα function.
In fact, increased plasma values of NGAL, suggestive for AKI, were found in a high percentage of CKD patients with stably impaired renal function.
We have previously reported that stably transfected RB functions as a growth and tumour suppressor in HTB9 human bladder carcinoma cells, which carry a mutation of the p53 gene at codon 280 and lack RB expression.
We showed by 2D-gels that residents NUMTs, stably integrated in the nuclear genome, appear to function as late replication origins.
In HeLa cells, we also stably expressed a KLHDC8B-GFP fusion protein, which functioned in a dominant-negative role.
This shorter isoform can stably interact with DNA and, depending on promoter-context, can function as transcriptional repressor or activator [ 21, 22].
