To test whether the increased TRAIL-R2 levels could prime the cells for increased TRAIL responsiveness, we generated stable TRAIL-R2 and as controls TRAIL-R1 knockdown clones in HCT116 cells, labeled HCT.shDR5 and HCT.shDR4, respectively.
Existing instruments are designed to measure generally more stable, trail-like cognitive engagement, which means that the grain size of these instruments is too large to pick up fairly small contextual variations.
Given De Rossi's love of horses, there would also be an equestrian element, with stables and trail rides through the mountains.
We had just arrived at her favorite part on the trail; a stable with horses and a goat.
Although BimEL levels remained stable in doxorubicin- or TRAIL-stimulated cells, combined treatment with doxorubicin and TRAIL resulted in the disappearance of BimEL, indicating consumption of Bim in dying cells.
Neptune has a number of known trojan objects occupying both the Sun Neptune and Lagrangian points gravitationally stable regions leading and trailing Neptune in its orbit, respectively.
Neptune possesses a number of trojan objects, which occupy its L4 and L5 points; gravitationally stable regions leading and trailing it in its orbit.
They designed a two-mass-skate bicycle that the equations of motion predict is self-stable even with negative trail, the front wheel contacts the ground in front of the steering axis, and with counter-rotating wheels to cancel any gyroscopic effects.
Jupiter trojans are located in either of Jupiter's L4 or L5 points (gravitationally stable regions leading and trailing a planet in its orbit); the term "trojan" is also used for small bodies in any other planetary or satellite Lagrange point.
Other nearby amenities include hiking trails, stables, marinas and casinos.
Neighbors often congregate at Edgerton Park, a 22-acre gardenlike retreat that features walking trails, stables for the city's mounted police and summertime performances of Shakespeare.
