This module has the property of bistability, i.e. it has two stable steady state values for a particular range of the signal values and an unstable steady state as well.
In Figure 5 a one-parameter bifurcation diagram for both the slip and catch bond models shows the stable steady state values for the amount of focal adhesions resulting from the two different initial conditions as a function of the value of the parameter ρRHO, which describes the influence of the Rho-concentration on the force.
With the initial release of Cd2+ and PO4 3− was the fast increasing of the aqueous pH from 5.60 to 6.58 in the first hour of dissolution, and after that the aqueous pH reached a stable state with the values of about 5.50 6.60 after dissolution for 120 days.
Furthermore, if r 0 is large then there is only one stable state for all values of k, and this changes smoothly from dead to living as k is increased across the dotted line in Figure 1.
After idealizing the side-chain structures, the free energy is either improved by a relatively biger amount or worsened by a relatively smaller amount as shown in Figure 7. Unfortunately, in most cases, the free energy is worsened slightly but is still in a stable state with negative values.
At the single-cell level, it slows the switch dynamics in the high protein production regime and enlarges the difference between stable steady-state values.
It is proven analytically that IHDIC with serial update scheme always converges to a stable state in the estimated values in course of iterations and that IHDIC with parallel update scheme converges to cycles of length 2. Additionally, we visualize the convergence behavior with the aid of convergence charts.
Each type of DNA damage, described by the combination of the different levels of the input nodes DSB and SSB, defines a unique stable state, in which the values of the output nodes embody the cell fates ('proliferation', 'apoptosis', 'senescence'cycle_arrestest'cycle_arrest
It can be seen that the degradations of TBA and glucose take the similar time to achieve the stable state, but both the photocurrent values and the peak area of the I t curve obtained from TBA are significantly smaller than that of glucose.
In one, positive feedback gives rise to multistability, i.e., the existence of more than one stable state for the same parameter values.
