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A mechanically stable spine provides an ideal environment for the formation of a fusion mass.
A trade-off, hence, exists between lower muscle forces and spinal loads on one hand and more stable spine on the other.
The remaining patients attained a painless and stable spine immediately, which was maintained for long periods (mean follow-up: 25.4 months).
As the brain matures, these abundant and motile filopodia are replaced with more stable spine synapses [8].
Hoffman and Gabel [ 2] extended this model arguing that a stable spine is important for effective and injury-free movements of the limbs.
Patients were admitted to the program if they had a spinal cord injury, a stable spine and absence of a high-grade pressure ulcer.
Similar(49)
During development, dendritic filopodia show high motility and their numbers correlate inversely with the onset of more stable spines and synapses [2], [8], [28], [34], [42].
Moreover, the increased number of lost spines was due to the elimination of stable spines (data not shown).
These stable spines are considered to represent the structural basis for long-term information storage [ 2, 4].
Dendritic spines are highly dynamic structures that undergo cycles of extension and retraction, although as neurons mature more stable spines gradually replace motile spines.
In conclusion, we detected a disturbed spine turnover within the peri-plaque region that was caused by a loss of stable spines.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com