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We then pick as optimal the parameters leading to the most stable selection and report as finally selected the features selected in all folds.
We provide experimental evidence to support this generalization, and develop an automatic stabilization procedure based on local Lebesgue functions for the stable selection of stencil weights over a wide range of δ values.
The stable selection marker is puromycin.
Cells were transfected using Lipofectamine 2000 (Invitrogen) according to the manufacturer's instructions and stable selection was carried out using 0.5 µg/ml of G418 (Gibco).
As in MS and RO, the FR reward structure possesses a crossing point in the reward functions that acts as a stable selection strategy (Figure 1D).
Moreover, when we analyzed the levels of the different PrP constructs over time, we observed a decreased expression of PrPCTM or PrPPG14 after stable selection, whereas higher PrPD177N expression levels were maintained over time (Figure S4).
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In Section 4, we show that this Stable LASSO selection procedure performs better than simply choosing a small number of features (random selection) or choosing features based on their SVR weights (SVR selection) (see Fig. 7).
The manuscript Stable feature selection and classification algorithms for multiclass microarray data by Sebastian Student and Krzysztof Fujarewicz presents a new feature selection and multi-classification algorithm based on Partial Least Squares and decomposition into separate two-class problems.
Minority variants are shown to maintain a stable mutation-selection equilibrium under positive selection, particularly in the capsid gene region.
Minority variants are shown, furthermore, to maintain a stable mutation-selection equilibrium under positive selection, particularly in the capsid gene region.
For the steps of thresholding and stable segment selection, the computational complexity is O(mn).
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