Sentence examples for stable loss from inspiring English sources

A stable loss of function allele was generated with the TALEN genome editing system targeting an mwoI restriction enzyme site located within exon seven of gba1.

Weight change was categorized as weight loss (loss of ≥2 kg), stable (loss or gain of ≤2 kg), or weight gain (gain of ≥2 kg).

The stable loss of expression of CD26, a T-cell activation marker, in MF/SS suggests that this activation pathway may be nonfunctional in most MF/SS tumors.

Stable loss of methylation in HCT116 cells does result in a minor increase of several thousand binding sites, largely corresponding to selective reactivation of binding sites from other cell types, especially from other malignant cell lines.

At −18 °C, concentrations were stable (loss <15%%) for 84 days, both with and without NaF, and they were unstable at +4 °C, with a loss of 25 and 50 % by day 14, with and without NaF, respectively.

In 22Rv1 cells, similar to DU145 cells, stable loss of SPRY2 significantly enhanced cell growth as well as upregulated EGFR/HER2 phosphorylation along with PI3K/AKT activation as their downstream signalling partners (Supporting Information Fig S13).

Next up is the MongoDB IPO filing, which presents an interesting mix of revenue growth, persistent — if stable — losses, and a New York pedigree.

Recently, powerful genome-editing techniques have been developed to generate stable loss-of-function models for neurodegenerative diseases (Schmid and Haass, 2013).

In order to evaluate the stability of I-XCI in undifferentiated TS cells, we used a female TS cell line (F3) carrying a mutation at the X-linked Hprt locus (Hprt bm1 ) associated with a retroviral insertion in the maternal Hprt1 gene, which leads to a stable loss-of-function of the maternal allele [ 28].

In contrast, the toxicity of deoxyviolacein was not dose-dependent but led to fairly consistent and stable losses in the viability over a range of concentrations (0.1 10  μM).

Temperature stable, low loss dielectric ceramics find application as resonators in communication systems operating at microwave frequencies.