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Approximately equal numbers of participants became colonized with MRSA or were no longer colonized at each sequential study visit to maintain this stable colonization prevalence.
Temperate viruses can directly affect host gene pools by stable colonization.
Further, we present challenges faced by the community in the development of microbiome therapeutics, including designing microbial therapies that are adapted for specific geographies in the body, stable colonization with microbial therapies, discovery of clinically relevant biosensors, robustness of engineered synthetic gene circuits and addressing safety and biocontainment concerns.
Moreover, in two persons ESCREC strains were documented to persist for at least 6 days or 17 days, suggesting possible establishment of stable colonization.
The enrichment of antimicrobial peptide transporters and the multidrug efflux pump may play a primary role in the stable colonization of gut microbes in the adult intestine by conferring resistance to CAMPs.
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Thus, alternative stable states of colonization exist even in this low-complexity model of host-microbe interactions.
Colonization was stable during the first 3 sampling rounds and no seasonal effect on the prevalence of colonization was observed before conversion to monochloramine.
Consequently, they are relatively stable environments for bacterial colonization during biofilm development4, making the formation of dental calculus difficult to prevent without mechanical removal.
We further hypothesized that the ensuing dataset could be used to test the 'free-living stabilization hypothesis' (Fig. 1), in which free-living coral species establish stable substrate for coral colonization by settling and surviving on a mobile substrate as coralliths.
Rate of multiple colonization remained stable up to three years after PCV7 introduction.
Conversely, asexual reproduction may limit genetic variation and adaptive potential, but provides reproductive assurance in stable environments and during colonization events [18], [21], [22] (see also [23]).
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