Because they're such stable chemicals they perform really well, but they don't break down.
The main reagents used for the assay, hemin and DMSO, are stable chemicals and are very inexpensive, another advantage for high throughput screening.
PFAAs are exceptionally stable chemicals that have a very long degradation half-life in the environment.
The half-lives (DT50) in the carbamazepine and fluoxetine studies would suggest these are the most stable chemicals relative to the other chemicals assessed (Table 2).
Environ Health Perspect 123:1038–1045; http://dx.doi.org/10.1289/ehp.1408834 Perfluorinated chemicals (PFCs) are ubiquitous and stable chemicals widely detected in humans and environment.
Fluorinated organic compounds (FOCs), such as perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorooctane sulfonylamide (PFOSA), are stable chemicals with a wide range of industrial and consumer applications (Renner 2001).
Persistent organic pollutants (POPs) are a family of lipophilic stable chemicals that bio-accumulate in adipose tissue and create a lasting toxic body burden (Van den Berg et al. 2006).
