Sentence examples for stable bind from inspiring English sources

In the process of structural alignment and ligand mapping successively, ligand in template may not have a stable bind with unbound chain (Fig. 6a, b).

This suggests that only a fraction of the conformers of the inhibitors in solution adopts a conformation best suited for binding interaction with VanX and that the VanX inhibitor complex may concomitantly undergo a conformational isomerization from an initial but fast weak-binding adduct to slowly convert to a tight-binding complex with a more stable bound geometry.

Next, we mapped Sox2 EnC clusters by deploying low-excitation and long-acquisition times (2 Hz) for detecting stable bound JF646 HaloTag-Sox2 JF646 HaloTag-Sox2

Porous PPF-based scaffolds produced by deep-UV photocuring were coated by elastin and the functionalized scaffolds were extensively characterized, revealing a stable bound between the protein and the polymer surface.

Another interesting aspect of Figure 6 is that for d ≥ 7 the taxa counts saturate at about 60, providing a stable bound on the number of species that are expected to have quite large Hamming distances (over 150) between their relevant protein sequences.

The designs are hyper-stable, bind human and mouse IL-2Rbetagammac with higher affinity than the natural cytokines, and elicit downstream cell signalling independently of IL-2Ralpha and IL-15Ralpha.

Combining modelling, an improved FRAP methodology and direct semi-quantitative analysis of bleaching suggests the existence of two membrane-bound Dystrophin populations with widely differing bound lifetimes: a stable, tightly bound pool, and a dynamic bound pool with high turnover rate that exchanges with the cytoplasmic pool.

The scDR1αβ mutants displayed on the yeast cell surface are remarkably stable and bind specifically to DR-specific peptide HA306 318 with high sensitivity and rapid kinetics in flow cytometric assays.

The findings that myositis autoantibodies arise months prior to clinical disease onset, are antigen-driven and isotype-restricted, have stable spectrotypes, bind to conformational rather than linear epitopes and inhibit the function of their targets, however, all suggest inherent differences in how immune systems respond to autoantigens versus injected antigens [ 10, 11].

The increase in Bmax suggests that a shift of the binding equilibrium occurs toward a stable ligand bound state for GluN2A, with a slower ligand dissociation rate.

The unpopularity of marriage and the relative ease of divorce has left only a hard core of stable couples bound in wedlock.