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Although transiently stable, keratin will eventually revert back to the more thermodynamically stable alpha form.
It would still not allow individual monomers to be infectious as they revert back to the more stable alpha form.
However, the formation of stable alpha phase alumina on metallic substrates at lower temperatures still presents technical challenges.
X-ray diffraction showed that stable alpha alumina dominated in the top alumina layers, while γ-Al2O3 and β-Al2O3 were also detected.
Rather, the stable alpha helices inhibited the types of interaction that would otherwise lead to amyloid formation.It has been known for a long time that mutations in a protein can encourage amyloid formation.
Especially for alpha oscillations, recent evidence for a functional role of stable alpha oscillations in memory has been reported.
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Main, E. R. et al. Design of stable alpha-helical arrays from an idealized TPR motif.
The stable alpha-alumina scale, formed on the bond coat surface prior to TBC deposition, is less susceptible to separation along the TBC TGO interface and also exhibits a lower growth rate in comparison with the TGO that develops on a similar bond coat without pre-oxidation.
The secondary structure of E2-2 wanalyzedzed with online server-Jpred4, and the amino acid sequence from 362 to 671 with three predicted stable alpha-helix domains was selected as immunogen (http://www.compbio.dundee.ac.uk/jpred4/index.html).html
However another similar 16-residue peptide with the same amino acid composition with i, i+3 and i, i+4 arrangement, but with different sequence was again found to form an exceedingly stable alpha-helix [15], [16].
This design was predicted to form a stable alpha-helical structure in solution (Marqusee and Baldwin, 1987).
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