Dynamically, the aluminate-silicate chains, calcium ions and functional hydroxyl groups establish the "cages", and strongly prevent the freely diffusion of the interface water molecules, stabilizing the connections between CSH and GO structures.
Keeley, DP, and Sherwood, DR. "Type IV Collagen stabilizes the connection of juxtaposed tissues at the B-LINK complex". 2016.
For instance, BamD stabilizes the connection between POTRA-5 and the β-barrel, as well as the POTRA1 2 connection.
In vivo, NL2 would then recruit further postsynaptic density proteins (Poulopoulos et al., 2009), and perhaps this, together with the increased synaptic activity, would further strengthen and stabilize the connection (Hartman et al., 2006; Varoqueaux et al., 2006; Chubykin et al., 2007).
Rtls may stabilize the connections between rosette cells by interacting with the ECM in a manner akin to the lecticans, a family of animal C-type lectins that stabilize cartilage and other connective tissues by cross-linking carbohydrates and proteins in the ECM (Ruoslahti, 1996).
These observations led to the hypothesis that filopodia may initiate synaptogenesis by extending themselves towards axons and, subsequently, stabilizing the resulting connections into mature synapses [43].
In addition, BamB stabilizes the POTRA2 3 connection, and BamE, together with BamD, stabilizes the POTRA4 5 connection.
Thus, the multiple connections stabilizing the Hin tetramer onto the Fis/enhancer element function to restrict processive subunit exchanges.
Hair-cell activity would subsequently stabilize the synaptic connections over a period of several hours.
Stabilizing the patient is the first priority.
