Sentence examples for stabilizing its activity from inspiring English sources

Using a therapeutic agent, ACT1, that targets endogenous Cx43 by stabilizing its activity at gap junctions, we show that modulation of Cx43 signaling alters breast cancer cell proliferation in the MCF7 and MDA MB 231 cell lines.

Within 165 h' test, the sample stabilized its activity for DMO and selectivity toward MEG all the time.

In this study, we found that E3 ligase UHRF2 ubiquitinated TIP60 and further stabilized its expression and elevated its activity via RING finger domain in normal cells.

After induction, HIPK2 is temporarily stabilized and its activity may be regulated by caspase-mediated removal of an autoinhibitory domain, resulting in its hyperactivation.

The final step is the ligation of the two DNA ends by DNA Ligase IV, which acts in a complex together with XRCC4 and Cernunnos/XLF that stabilize it and stimulate its activity (for review see[3], [4]).

This interaction resulted in a more stabilized enzyme with its activity [41].

Apparently, in the case of Pax6 initial Jmjd3 recruitment is without consequences on H3K27me3 levels and complete demethylation is observed only in NS cells, possibly to stabilize and sustain its activity.

RING K65 sumoylation is unessential for NB-biogenesis (Supplementary Figure 6d), but could stabilize UBC9 binding2 and favor its activity towards other PML sites, notably K160.

XRCC4 stabilizes LIG4 and enhances its activity.

Functional characterization revealed that EL1, which encodes a casein kinase I, could phosphorylate the rice DELLA protein SLR1 in vitro and in vivo, stabilize SLR1, and sustain its activity in vivo, to negatively regulate the GA signalling.

Such altered subcellular localization of HuR has been shown to correlate with its mRNA stabilizing activity [4].