Sentence examples for stabilizing contacts from inspiring English sources

Comparing the structures revealed that the network of stabilizing contacts between the UPA C11 aryl group and the LBD is responsible for its high PR antagonist potency.

The data show that the loss of native stabilizing contacts during activation is compensated by non-native transient atomic interactions during the transition.

The complexing agents or binders may be cyclic or open-chained but successful binders must be organized either by design or by conformation to provide stabilizing contacts with anions having a range of geometric features.

There also are unique stabilizing contacts between the 15α-hydroxyl on 15α-OH-E2 and Met-406 and Met-409.

There are, however, other unique stabilizing contacts between Met-409 on lamprey ER and C15 on E2, which could compensate for the loss of the hydrogen bond between His-509 and the 17β-hydroxyl on E2.

Additionally, we show that the C-terminus of CKIε can positively regulate substrates by stabilizing contacts with the kinase domain when dephosphorylated, whereas it can negatively regulate substrate-kinase interactions when autophosphorylated.

However, after energy minization, Asn564 moved and lost its stabilizing contact with the C11 hydroxyl on dexamethasone (Fig 8B).

Together, these findings provide a novel mechanism by which NLG-1 could form dendritic spines by promoting filopodia extension and stabilizing contact with a presynaptic terminal.

Also considered is the role of HK2 binding in stabilizing contact sites between the OMM and the inner membrane.

Mutation of Arg160 would remove a stabilizing contact with the phosphoryl oxygens, likely making the loop more flexible.

In every case, the native amino acid was mutated to a smaller side chain (usually alanine), thereby removing the potential stabilizing contact without introducing steric clash.