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While self-association is not necessarily a prerequisite for activity, the active sites of perhaps one-sixth of all oligomeric enzymes are located at highly stabilized interfaces between two peptide chains.
The core serves as a nonaqueous reservoir for hydrophobic drug, and the shell interacts with the biological environment and serves as a stabilizing interface between the hydrophobic core and the external medium.
Thus, similar interface properties can be assumed for all nanocapsules, suggesting that molecules of Cremophor EL® probably stabilize interface of studied systems by steric repulsions of the Stern layer [ 38].
In contrast, P2 and P3, located in the most stable region of tropomyosin, have stabilizing interfaces.
Alternatively, ISRIB may stabilize interfaces between eIF2B4 in one eIF2B pentamer and eIF2B2 in an opposing pentamer.
Stabilized BN interface had modified the fiber matrix interfacial bond strength to 9 MPa and improved the toughness.
As compared to the enhanced material structure, the stabilized electrode/electrolyte interface is the primary factor contributing to the improved electrochemical performance.
The CT domain contributes the side chains of Glu711 and Glu712, forming charged 'fingers' that dip into the cavity lining the dimeric motor interface to further stabilize the interface.
Recent experimental and theoretical findings suggest that nanocrystalline binary alloys can be stabilized against interface-driven homogenization processes via grain boundary (GB) solute segregation mechanism.
Other exchange events lead to aberrant structures that are stabilized via interfaces comprised of many of the same residues that are involved in inter-molecular interactions in the native dimer.
In stabilizing the interface, mutation is done in the interface for forming an ion pairs between the monomers.
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CEO of Professional Science Editing for Scientists @ prosciediting.com