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Damage stability regulation is one of the most important safety issues.
This novel mechanism for TAZ stability regulation indicates that TAZ might be a crucial oncoprotein which acts downstream of the PI3K/AKT pathway during tumorigenesis.
Taken together, the N-terminal and C-terminal phosphodegrons of TAZ which are responsible for the stability regulation of TAZ are differently modulated by the PI3K/AKT and the Hippo signaling pathways, suggesting that the protein level of TAZ can be manipulated in response to a wide range of intrinsic and extracellular signals through these two pathways.
Therefore, we can conclude that about 62% of the yeast genes undergo significant mRNA stability regulation during the heat shock response.
The ability to produce acetylated protein will now allow more detailed studies of the role of protein acetylation in protein stability, regulation of structure and function, as well as allowing the generate low cost proteins and peptides for the biotechnology & pharmaceutical industries.
Another important posttranslational regulation is protein stability regulation.
Similar(34)
Even the tough post-crisis financial stability regulations passed in the UK and the USA do not stipulate the need to pursue a mixed economy of banking.
"We would like to think we could develop an appropriate set of financial stability regulations to apply to all Premier League clubs.
Present stability regulations developed over the years by IMO reached definite conclusion with the adoption of the Revised draft of the Intact Stability Code.
The current IMO resolutions contain two different probabilistic damage stability regulations: A.265 for passenger vessels and SOLAS Part B-1 for dry cargo vessels.
This paper focuses on ship stability regulations laid out in the Directive 2006/87/EC in relation to the safety of shallow-draught inland container vessels designed for the Danube.
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