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The thermal stability of compounds at the sintering temperature must also be taken into account.
Rates of metabolism in human hepatocyte suspensions provide useful information on the stability of compounds that undergo a first pass metabolism.
2D fingerprint plots have been used to quantify the relative contribution of the intermolecular contacts to crystal stability of compounds, showing the crucial importance of weak interactions in building different supramolecular architectures.
The high fluorescence quantum yields, desirable the highest occupied molecular orbital levels and high thermal stability of compounds 9 13 indicate that the linkage of triphenylpyridine and triphenylamine is an efficient means to enhance hole-transporting ability and fluorescent quantum yield.
This result is related, as also shown by DTA measurements, to an increasing stability of compounds richer in zinc, to increasing covalent effects and/or to less octahedral site distortion around the metal atoms when zinc substitutes Cu2+ ions in the malachite structure.
The temporal stability of compounds trapped on Tenax TA and the formation of artifacts from degradation of the adsorbent Tenax TA is widely discussed in literature [16], [17], [18] – the main degradation products are known as Benzaldehyde, Acetophenone and Benzoic acid and to a minor extent Benzene, Toluene and Xylenes.
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The thermal stability of compound 1 both for its crystals and nanostructures has been studied by the thermal gravimetric (TG) method and compared with each other.
The stability of compound 9 in simulated vaginal fluid (SVF) was performed via HPLC-PDA method, which supported its utility for vaginal administration.
Therefore, improving the thermal stability of compound cannot be achieved simply by increasing the number of substituents on the benzene ring.
A linear stability analysis of the viscous flow regime indicates that the stability of compound jets is governed by the same eigenvalue equation as that for the spinning of round fibres and annular jets.
The objective of this study was to develop a deep understanding of the stability of compound A based on its degradation kinetics and mechanism to enable design of a robust drug product.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com