Sentence examples for stability of client from inspiring English sources

In addition to a direct role in stability of client proteins, hsp90 also functions in protein turnover mediated by the chaperone-dependent ubiquitin E3 ligase, CHIP [16].

These data suggest that TRAP1 does not influence long-term stability of client proteins.

These mechanisms include their molecular chaperone activity, anti-apoptosis function and influence on the stability of client proteins [ 26].

Turning to the stability of client ratings over time, those studies that assessed satisfaction at multiple treatment stages (n = 10, see Additional File 2) reported no significant changes in ratings across assessment points.

We looked at many aspects of the firm including, but not limited to: sources of revenue, stability of revenue, client base, cost structure and profitability of the firm, historical returns of their investment products, their investment process, legal structure of the firm and the investment, key professionals at the firm, legal and compliance practices.

The ATPase cycle of the Hsp90 molecular chaperone is essential for maintaining the stability of numerous client proteins.

Since Hsp90 is a molecular chaperone that regulates the maturation, activation and stability of numerous "client proteins" including ALK, dual targeting ALK and Hsp90 may bring more benefits and efficacy against drug resistance of ALK inhibitors.

Hsp90 inhibitors reduce the stability of associated client proteins, and may thereby exert anti-oncogenic effects.

HSP90 is a molecular chaperone essential for the stability of nascent client proteins involved in signal pathways controlling cell physiology.

By decreasing the abundance of HSP90AA1 in cancer cells, 2-24a/Cu couldecreasese the stability of HSP90AA1 client proteins, many of which are critical in tumor initiation and metastasis.

We sought to determine whether UGT1A-mediated resistance to ganetespib is also mediated by maintaining the stability of HSP90 client oncoproteins.