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Paired PB/SF or ST samples were analysed using either paired t or Wilcoxon signed rank matched pairs tests.
RA synovial tissue (ST) samples (n = 3) were collected from patients with erosive, end-stage RA at the time of joint replacement surgery.
Other studies also report that IL-17+ T cells or IL-17 mRNA are not universally present in RA ST, and are found in 28 60% of RA ST samples [12], [23], [28].
ST samples were counterstained with Harris hematoxylin.
Deiminated fibrin was evidenced in all of the ST samples.
In contrast, IL-22 expression was not expressed in any of 11 PsA ST samples, but was expressed in seven of eleven of the RA ST samples.
ST samples were retested on Days 3, 5, and 7. Nineteen ST samples were stored for an additional week and retested on Day 14.
CD4+ T cells were isolated from ST samples, as previously described [ 27].
Fut1 expression was determined in RA ST samples by immunohistological staining.
We extracted DNA from ST samples from 28 patients with arthritis.
NGF expression was higher in ST samples of RA as compared to SpA.
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