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During the conditioning phase, animals received 5 mg/kg of MDMA plus 3 mg/kg of SR alone or plus 0.1 mg/kg of WIN (MDMA 5 + SR 3; MDMA 5 + SR 3 + WIN 0.1); or 1.25 mg/kg of MDMA plus 3 mg/kg of SR alone or plus 0.1 mg/kg of WIN (MDMA 1.25 + SR 3; MDMA 1.25 + SR 3 + WIN 0.1).
8.27am GMT Here is the leaderboard after the first run of the women's skeleton 1 Elizabeth Yarnold (Britain) 58.43 seconds TR 2 Elena Nikitina (Russia) 58.48 sec SR 3 Noelle Pikus-Pace (U.S).
From there, SR 3 runs concurrently with SR 299 north to the town of Weaverville.
The first exit is SR 3, a partial cloverleaf interchange with service roads.
SR 305 continues northwest through Poulsbo, intersecting SR 307 and ending at the SR 3 freeway.
The highway continues northwest to end at a partial cloverleaf interchange with the SR 3 freeway north of the city.
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A total of 636, 2,464 and 2,041 unigenes showed differential expression in the comparison of SR-1 vs SR-2, SR-2 vs SR-3 and SR-2 vs SR-3.
For each genotype, the expression of 141, 144 and 144 UGTs (RPKM >0) were detected in SR-1, SR-2 and SR-3, respectively (Additional file 12).
Surprisely, the GGDPS gene, involved in the biosynthetic pathway of an SG precursor (geranylgeranyl diphosphate) was hardly detected in SR-1, SR-2 and SR-3.
DXS, MDS, HDS, KO, UGT85C2 and UGT76G1 were highly expressed in SR-1, SR-2 and SR-3 and showed obvious differences in expression among the three genotypes.
Furthermore, one, two, and nine UGTs were specifically expressed in SR-1, SR-2 and SR-3, respectively (Red UTGs in Additional file 12).
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