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While confabulation is pathological by definition, all people include an inventive (and thus spurious) element in their remembering.
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We show that the statistical significance assigned to each CpGcluster island is a key criterion to control the overlap with promoter regions, evolutionarily conserved elements and spurious Alu elements.
We determined the overlap of CGIs with conserved elements (PhastCons) and spurious Alu elements.
The cpgISg predictions show the highest overlap with the promoter region (R13), and conserved PhastCons elements, simultaneously showing the lowest overlap with spurious Alu elements.
The island sets selected by p-value clearly outperformed those selected by length: a higher percentage of CpGcluster islands overlap with promoters and PhastCons elements along the entire range of the two parameters, at the same time reducing the overlap with spurious Alu elements.
Some spurious absorbing elements (most likely small skull bone fragments due to imperfections in the surgical excision of the brain) can be noticed in the reported projection.
Prediction quality has been assigned conventionally by the percentage of overlap with promoter regions and spurious Alu elements.
Subsequently, this threshold was increased to 500 bp in order to reduce the false positive rate by eliminating spurious Alu elements [ 21].
The above sequence was chosen to provide enough degeneracy to identify all "true" STAR elements conforming to the original description from Cramton et al. [ 1], and as used in the MVLA schemes [ 13- 15] while limiting the identification of spurious STAR elements.
The Cardinal has called for a public inquiry into the leaking of these spurious claims by elements in the Victorian Police in a manner clearly designed to embarrass the Cardinal, in a case study where the historical failures of the Victorian Police have been the subject of substantial evidence.
We then manually inspected all roo elements for spurious hits.
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