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Depleting the cell glycocalyx with protease treatment enhances the spreading response in sheared leukocytes.
The spreading response requires an intact actin network and activated myosin molecules.
We next cultured corneal fibroblasts within and on top of standard collagen and fibrin matrices to assess the impact of ECM composition on the cell spreading response.
The quantitative analysis results of the azimuth point spreading response functions of Fig. 9 are listed in Table 4.
Moreover, in order to check the azimuth point spreading response improvement of the one-step MOCO-based imaging algorithm, two isolated point-like targets named point A and point B are extracted from Fig. 7 by yellow circle for azimuth point spreading response function comparison.
This spreading response is not due to changes in the chemical nature of the substrate or the stiffness of the individual fibrils.
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Muskelin is a member of the kelch-repeat superfamily of proteins, identified as an intracellular protein involved in cell spreading responses to thombospondin-1.
We demonstrate that as compared to pure GelMA, GelMA polyaniline (GelMA Pani) composite has similar swelling properties and compressive modulus, comparable cell adhesion and spreading responses, and superior electrical properties.
Each of the three NP-TGT sensors producing mechanical forces at 12, 43, or 56 pN similarly drove the cells to undergo spreading responses and the synaptic accumulation of BCRs or pSyk signaling molecules into the IS.
Cell spreading responses to HGF are concentration-dependent for both PC3 and C4-2 prostate cancer cell lines, but an effective dose 50 (EC50) for PC3 cells is achieved at a lower concentration (5 ng/ml) than for C4-2 cells (30 ng/ml).
10 And Sardenberg et al state "It should be emphasised that surgery does not change the biology of the tumor or the metastatic process, and a definitive cure for most patients represents the combination of host histology, tumor spread, response to systemic therapy, and surgical resection, which together render the patient free of disease".
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