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Even the most notorious hazardous-waste dumps on land pale beside the prospect of cleaning up miles of riverbed — in which the slightest movement can stir up long-buried wastes that tides, floods, even motorboat traffic can spread upstream and down.
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For a flow of moving bodies, congestion spreads upstream: this phenomenon is called spillback.
However, recently eutrophication of the Nakdong River, which was limited to the lower reaches, is seen to be spreading upstream.
Further analysis revealed that the methylation signal spreads upstream of the promoter.
The large scale impact is distributed and may spread to upstream transmission network.
After ignition, the flame initially spread only upstream, in a fan-shaped pattern.
Yet without it, Europe has no chance of getting gas from any source eastwards that doesn't cross Russian territory, with all that this entails.The story of Russian oil and gas businesses in the ex-communist countries is that influence spreads from upstream to downstream, from transit to distribution, and from business to politics.
The second class of conserved MGLCs are spread somewhat further upstream from the TSS (see Fig 3C).
The fitted curves were positioned mainly in the 500 bp central region with slight spread 100 bp upstream or downstream from the center, indicating that the nrpe-directed suppression is concentrated within each 500 bp regions we selected.
This would allow the upstream spreading of heterochromatin from the expanded GAA triplet-repeat in FRDA patients, thus resulting in FXN transcriptional deficiency.
89, 93 Later, aberrant DNA methylation takes place at CpG residues within CGG repeats and spreads to the upstream promoter region, 92 preventing the binding of transcription factors such as α-PAL/nuclear respiratory factor 1 (NRF1), that are required for FMR1 expression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com