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10 And Sardenberg et al state "It should be emphasised that surgery does not change the biology of the tumor or the metastatic process, and a definitive cure for most patients represents the combination of host histology, tumor spread, response to systemic therapy, and surgical resection, which together render the patient free of disease".
Those variants represent distinct diseases, as supported by differences in epidemiology, genetic risk factors, molecular events, premalignant lesions, patterns of spread, response to chemotherapy, and prognosis [ 8].
However, despite taxonomic efforts, EOC appears to be not a unique disease; its subtypes differ for epidemiological and genetic risk factors, precursor lesions, patterns of spread, response to chemotherapy, and prognosis.
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A comparison of scores, facility, discrimination, reliability and validity from 3-, 4- and 5-option versions of the multiple choice test found little variation in the performance of the three option formats although higher numbers of options tended to increase difficulty and to spread responses between the options.
Depleting the cell glycocalyx with protease treatment enhances the spreading response in sheared leukocytes.
The spreading response requires an intact actin network and activated myosin molecules.
The quantitative analysis results of the azimuth point spreading response functions of Fig. 9 are listed in Table 4.
We next cultured corneal fibroblasts within and on top of standard collagen and fibrin matrices to assess the impact of ECM composition on the cell spreading response.
Moreover, in order to check the azimuth point spreading response improvement of the one-step MOCO-based imaging algorithm, two isolated point-like targets named point A and point B are extracted from Fig. 7 by yellow circle for azimuth point spreading response function comparison.
This spreading response is not due to changes in the chemical nature of the substrate or the stiffness of the individual fibrils.
We checked this hypothesis by studying the fraction of cells that displayed a spreading response.
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