The structure described herein is homologous to a target in wide-spread pathogenic (toxin producing) bacteria such as Clostridium tetani (64% sequence identity) suggesting the potential of the structure solved here to be applied for modeling drug interactions.
While antibody-based vaccines are the only current means by which to provide sterilizing immunity, a vaccine to reduce the morbidity and mortality associated with a rapidly spreading pathogenic virus would be a valuable tool in combating a pandemic.
Chilean R&D centers studied copper's ability to limit the spread of pathogenic microorganisms.
Recent outbreaks of WNV associated with the introduction of lineage 1 strains into the western hemisphere, together with the emergence of lineage 2 WNV in Central Europe, has highlighted the potential for spread of pathogenic WNV strains beyond their expected geographical boundaries.
As a relatively cost-effective preventive measure they can help to avert transmissible diseases and thus protect not only the vaccinated individuals but also those who have not been vaccinated, by containing the spread of pathogenic agents [1, 2].
In human environments, however, it results in the undesirable spread of pathogenic, antibiotic resistance, or artificially engineered genes [2], [4] [8].
The mucilage can act as a controlling factor of microbial diversity across wide oceanic regions and could have the potential to act as a carrier of specific microorganisms, thereby increasing the spread of pathogenic bacteria.
These plasmids are a snapshot of how easily resistance genes are gained and spread among pathogenic staphylococci.
Studies do not support the claim that migratory birds can spread highly pathogenic avian influenza (H5N1) over long distances.
This may involve neurotrophic factors withdrawal, aberrant neurotransmission, synaptic loss, excitotoxicity and prion-like spread of pathogenic misfolded proteins like trans-synaptic spread of Aβ [ 3].
