Exact(2)
Consequently, determining P. aeruginosa acquisition pathways and conducting longitudinal surveillance using molecular-based typing techniques are critical steps for developing novel interventions and evidence-based infection control policies to interrupt the spread of transmissible strains within the CF community [ 4- 6].
While a number of studies suggest rapid diversification of phages, e.g., through recombination [ 50, 51], our data suggest that at least some phage groups are relatively stable at the genomic level and also suggest that phage dispersal could contribute to global spread of transmissible genomic elements, including those encoding resistance and putative virulence genes.
Similar(58)
These results could impact our understanding of all phenomena driven by face-to-face interactions, such as the spreading of transmissible infectious diseases and information.
For example, if TB is growing disproportionately compared to HIV (indicated by a high value of RTB/HIV), possible causes could include social conditions linked to poverty, malnutrition and high population density, which can boost TB transmission, or else the spread of more transmissible and virulent TB strains.
"The unit staff is trained in strict infection control practices optimized to prevent spread of potentially transmissible agents such as Ebola".
In the second scenario, not only are clinical infections reduced, but also the spread of highly transmissible resistant viruses is prevented.
However, aggressive treatment above the optimal level can substantially promote the spread of highly transmissible resistant mutants and increase the total number of infections.
The spread of a transmissible disease in a host population is a dynamic process where the probability of individuals becoming infected depends on the number of infected individuals in their neighborhood.
This may be due to the longer surveillance period used here, as well as to endemic spread of highly transmissible strains, including several of the Beijing family.
Genetic analysis on microsatellite and DLA alleles indicate that CTVT most likely originated in wolves and it has been hypothesized that the inbred nature of some wolf groups might have facilitated the initial spread of this transmissible cancer, similar to the facial tumour in Tasmanian devils [ 4].
In particular, the spreading of a transmissible disease can be studied by modeling the population as a network of individuals, in which an edge is placed between two individuals if there is the possibility of transmission between them.
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