Sentence examples for spread of infectivity from inspiring English sources

This suggests an incubation-period related centrifugal spread of infectivity from the brain and associated PrPd accumulation through the nervous system.

Thus, the timing and pattern of plaque distribution after microinjection of tg44 mice with RML scrapie supported our previous hypothesis that spread of infectivity occurred via dissemination with brain interstitial fluid (ISF) in perivascular regions of gray and white matter and in interaxonal spaces of white matter tracts [ 31].

Based on the preceding experiments, to study the spread of scrapie infectivity within the CNS more precisely, we infected mice i.c. using stereotaxic microinjection into the striatum using a 0.5 μl volume of scrapie brain homogenate (400 ID50) over 2 minutes.

Our results on studies of mice after intravenous scrapie inoculation did not support the suggestion of hematogenous spread of scrapie infectivity and PrPres (Table  4).

Scrapie prion accumulation was present in all scrapie retinas, and both the marked loss of photoreceptors and bipolar cells and the strong PrPSc staining within the central retina were consistent with a centrifugal spread of scrapie infectivity.

The simple simulations of the spread of infection on the networks indicate that there are typical behaviours, such as extinction of an epidemic at low infectivity but persistence at high infectivity.

One possible explanation for the reduced infectivity and spread of Kim53ΔJ+P following s.c infection is that this strain kills the transporter immune cells and thus prevents dissemination.

Those migrant workers with TB who experienced treatment delays, dropped out of therapy, or had therapy interrupted were likely to increase the period of infectivity and spread TB to other persons.

And HIV-infected children may have prolonged shedding of measles virus increasing the period of infectivity and the spread of measles virus to secondary contacts [ 21].

This localized spread together with the higher estimated level of infectivity in cattle after 31st March explains the long tail of the epidemic seen in 2001.

Our results clearly indicate that R88 delivers A3G into Vif+ HIV-1 particles and inhibits infectivity and spread of the virions among CD4+ T cells.