Sentence examples for spread of dna from inspiring English sources

With the spread of DNA sequence data, models of DNA sequence evolution rapidly proliferated.

The spread of DNA replication likely represents a major evolutionary transition in early life.

Previous studies in our laboratory showed that silencing of an integrated Aprt transgene allows the spread of DNA methylation into a promoter region, which stabilizes the silenced transcriptional state [4].

Similarly, the spread of DNA methylation might require read-through transcription for the primary substrates.

The spread of DNA methylation to adjacent parts of the RNA-DNA homology region has previously been documented (Wasseneger 2000).

In non-neoplastic cells the multifunctional CCCTC-binding factor (CTCF) can serve as a barrier against the spread of DNA methylation and histone repressive marks into promoter regions of tumor suppressor genes such as BRCA1, Rb, p16 and p53.

Daxinger, L. et al. A stepwise pathway for biogenesis of 24‐nt secondary siRNAs and spreading of DNA methylation.

Similarly, histone H3 acetylation has been shown to establish a protective boundary against spreading of DNA methylation [10].

However, in cancer, processes related to cell-selection might be involved in a progressive spreading of DNA methylation [35], [36], [37].

Therefore, we suggest that these zinc finger DNA binding proteins are likely to play essential roles in blocking the spreading of DNA methylation and protecting the U-CGIs from being methylated.

Amplification and diversification of the Mecp family in vertebrates coincided with the spreading of DNA methylation across the genome, and likely contributes to a 'fine tuning' mechanism of gene expression [53], [54].