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The simulations were used to (i) evaluate the effects of covariates, (ii) determine the spread of concentrations and approach to steady-state, and (iii) compute steady-state PK parameters, such as AUCτ, Cmax, and Ctrough.
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We note that linear regression should offer the greatest benefit where the data contain a wide spread of glucose concentrations; as we noted above, this is not the case for our living-subject data with its relatively narrow range of physiological blood glucose values and relatively high noise level.
They were unable to demonstrate a difference in EBC H2O2 between exposed and non-exposed children, though commented that low sensitivity of the assay, and wide spread of measured concentrations of H2O2 might mask subtle effects on airway inflammation.
On a logarithmic scale, the spread of maximum concentrations was reasonably modelled by a mixture of two normal distributions with means of -0.4 and 0.8 (corresponding to approximately 0.4 mM and 6.3 mM respectively) and standard deviations of 0.35.
The spread of measured concentrations for DCVG were captured by the Monte Carlo analysis at 2 hr, but with approximately 50% of the strains falling below the distribution of the simulations.
A comparative analysis of contaminant scenario can be made through analyzing the concentration at the source and the spread of this ideal concentration through various methods in the model environment with that of observed contaminant scenario to make comparative analysis of possible scenarios of contaminant in the real world.
Meanwhile, high mobility of Zn, Cd and As under basic conditions and a low Fe concentration explain the broad spread of these elements, as high concentrations were detected in soil more than 2000 m from the source.
Although Fig. 1 indicates a fairly good spread of data, low serum concentrations in these groups might have limited the ability to uncover significant associations, and possibly also the relevance to a broader population receiving mood stabilizers.
Furthermore, the spread of the observed soil solution concentrations was much larger than the spread in modelled concentrations (Fig. 4), especially for the pH and the NH4 concentration.
It is shown that the correlation is not insensitive to elevation and that it is dependent on three key parameters, that is, angular spread (concentration of scatterers within a cluster), mean AoA in azimuth and elevation, and position of the elements.
1. Spectrum broadening of QDs distribution that arise from inhomogeneous spread effect, concentration of crystalline defect, and inhomogeneous environment 2.
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