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Thus, viral gene expression increased with time due to more genomes reactivating and to some lytic spread from cells in which reactivation had already occured.
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How do viruses spread from cell to cell?
Viruses spread from cell to cell through trigger waves, so it makes sense that our initial line of immune defense might employ the same tactic.
Hunter is uncovering specific mechanisms that allow RNAi effects to spread from cell to cell, while Kunes is inventorying molecules that control olfactory learning in Drosophila.
The embryos were then restored to a constant temperature, and Graham and Lendert looked to see whether the desynchronized cells would come back into sync, as would be expected if cell cycles can spread from cell-to-cell.
She uses the approaches of molecular genetics, cell biology and genomics to understand how plant viruses use the cellular trafficking machinery to spread from cell-to-cell and invade the host plant.
Collectively, these findings suggest that amyloid conformers can spread from cell to cell within the brains of afflicted individuals, thereby spreading the specific neurodegenerative phenotypes distinctive to the protein being converted to amyloid.
Block integrase, the logic went, and the virus could not spread from cell to cell.
"There was a lot of skepticism, but then other labs showed α-synuclein might spread from cell to cell," Dawson says.
The research team has identified a protein that enables a toxic natural aggregate to spread from cell to cell in a mammal's brain, the process by which some scientists believe Parkinson's disease progresses.
They manipulate adjacent cells to form cell-cell adhesions (known also as viral synapses) to spread from cell-to-cell.
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