The AKT serine-threonine protein kinases exhibit a wide-spread expression pattern in virtually all human cell types.
As more Antarctic transcriptomes become available it will be possible to determine how wide-spread altered expression patterns, gene duplication events and even altered cellular networks are in Southern Ocean or indeed, polar animals.
In arthritic synovial tissue, the E-cadherin expression pattern was more widely spread, possibly due to hyperplasia (found in all patients).
First, enhancer trap lines that are spread over large distances often produce the same expression pattern, whereas other located just a few kb away produce a different pattern.
GmMADS3a (Glyma10g38580) exhibited a rather similar expression pattern to GmAP1 on 4SD, but its expression subsequently spread to the entire inflorescence meristem as well as to the newly established floral meristems on 6SD.
On the contrary, DNs and BCs, labelled with anti-phospho-S6 ribosomal protein antibody, were spread throughout the cortex without any apparent rule and showed a highly variable LSG expression pattern.
While all the EGFP-injected embryos showed unaltered wild-type or shh−/− mutant patched1 expression pattern (Fig. 6A, D, "low"), over-expression of dnPKA-GFP led to ectopic spreading of patched1 expression in 87,7 +/− 3,8% of embryos (Fig. 6A, D, "high").
In breast cancers, the expression pattern of CXCR4 showed a significant correlation with the degree of lymphatic spread but not with hematogenous metastasis.
Given the observed impaired recycling of β1-integrin, its accumulation in enlarged endosomes in CEDNIK cells (Figure 6) and the distinguishable expression pattern of FAK, PAX and their phosphorylated forms in peripheral adhesions (Figure 7), we examined the ability of CEDNIK cells to migrate and spread using wound healing and cell spreading assays.
Expression pattern of OsMYB61.
Fig. 4 Expression pattern of OsSND2.
