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An in vitro cell culture with osteoblast cells demonstrated that the electrospun composite mats possessed improved biological properties, including a better cell adhesion, spread and proliferation.
The in vitro biocompatibility evaluation with MC3T3-E1 cells using SEM, fluorescent staining and MTT assay revealed that the PBLG scaffolds had good biocompatibility and favored cell attachment, spread and proliferation.
Besides, Neutrophil a-defensins was found to localize in the junctional epithelium, which has significant effects on the epithelial integrity and functioning (keratinocyte adhesion, spread, and proliferation), and the effects are beyond their antibacterial activities [ 7].
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The hBMSCs show better cell morphology, adhesion, spreading and proliferation on CCHCs than on CHACs.
In vitro experiments demonstrated that the quinone groups on PDA greatly enhanced pre-osteoblasts MC3T3-E1 cell spreading and proliferation.
Cellular morphology and MTT assay revealed that nanofibers effectively support cellular attachment, spreading, and proliferation.
3D cellulose sponge exhibited the better cell infiltration, spreading and proliferation compared to 2D cellulose mat.
Recombinant human tropoelastin promoted primary human dermal fibroblast attachment, spreading and proliferation.
Fluorescence and confocal microscopy indicated normal cell attachment, spreading and proliferation on these biospun silk matrices.
The biological response of cells towards nanostructured PEEK was evaluated in terms of cell adhesion, spreading, and proliferation.
It has been observed that 13-nm-high islands inducellell spreading and proliferation, while 160-nm islands retard the attachment of filopodia.
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