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Some exceptional individuals, however, exhibit asymmetrical spot modifications (Fig. 2P-R).
Meanwhile, from an engineering point of view, multiple spot modifications can make the risks of system fluctuations or external impulsions more distributive than in the case that all alterations are concentrated on a single spot.
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Backstage, too, the actors were collecting and discarding props, making quick costume changes, at least one per person — and submitting to on-the-spot modifications.
In fact, it was such a rush job to get the E-Type race ready that Qvale's team made on-the-spot modifications (literally cutting holes in the car and welding on new parts) to save time during pit stops.
There's evidence that chiefs' compounds had metal workshops, making gold teeth a permanent mark of social distinction and allowing for constant on-the-spot modifications.
Hot-spots for modifications were found to be located in core regions of the ribosome, at the interface between the small and large ribosomal subunits and at sites of RNA-RNA interaction.
In several cases, PTMs could be recognized by horizontal or vertical shifting of a protein spot as these modifications usually change the protein MW and pI [ 11]. 2-DE gel easily and efficiently couples with many other analysis and biochemical techniques.
After several gut-wrenching weeks, the town's ad-hoc committee of 28 elected officials reached a unanimous decision to raze and rebuild Sandy Hook Elementary in the same spot -- with modifications.
ITA2B was overexpressed in the oligoarticular group as part of a 'charge train' of spots, strongly suggesting a process of serial post translational modifications.
We measured BPA, eight phthalate metabolites, and PA in the spot urine samples using modifications of established methods [ 24, 25].
The number and position of the detected spots reflect numerous posttranslational modifications of vimentin such as phosphorylation and citrullination, which have been previously described for this protein [44], [45], [46].
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