Sentence examples for spot deletion from inspiring English sources

Our studies indicated that relA and spoT deletion mutants of Y. pestis and S. Typhimurium have similar, but not identical, effects on growth and virulence.

Using colony probe hybridization to detect a common hot spot deletion, followed by polymerase chain reaction and DNA sequencing, we have generated 10 mutation spectra from three classes of mixtures (i.e., urban air, cigarette smoke condensate, and municipal waste incinerator emissions).

For example, in intron 44 there were 13 breakpoints resulted in the hot-spot deletion region [ 34].

Recently, Sanches-Cespedes and colleagues have identified a polyC mononucleotide repeat located between 303 and 315 nucleotides within the D-loop region as a mitochondrial hot spot of deletion or insertion mutations [ 7].

As Zhou et al. reported; the most frequent LOH was found in the 6q23.3-25.3 chregionmandregion and the second hot spot of deletions was located in the 6p21 region containing the major histocompatibility (MHC) classes I and II gene loci [ 22, 24].

With intent to analyze ATBF1-A mutations, we selected all the mutational spots in exon 9 and the most frequent deletion spot in exon 10 reported in prostate cancer because > 80% of the mutations reported in the paper were located in these spots (Table 2) [ 10].

Moreover, two hot spots of deletions were tentatively mapped on 11p13 and 11p15.5.

We selected all the mutational spots located in exon 9 and the most frequent deletion spot in exon 10 (Table 2), because > 80% of the mutations in the coding region of ATBF1-A gene reported in prostate cancer occurred in these locations.

The discrepancy of 16 Da is consistent with a loss of a hydroxyl group, indicating that after Dohh deletion, spot 2 consists of both the deoxyhypusine- and the hypusine-modified eIF5A.

Kuwahara et al. [ 39] identified a region between HER2 and GRB7 (a gene located 47 kb from HER2) that contains a recombinant hot spot for amplification, deletion and translocation.

Consistent with this idea, work in E. coli has shown that, in spoT and relA deletion mutants which are unable to produce (p ppGpp, RIFR mutations can decrease RNAP stability at promoters that are transcribed during rapid growth, thereby releasing RNAP for transcription at stringently regulated promoters.