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IOP fluctuates rhythmically with a 24-hour period (diurnal variation), but it also shows rhythmical fluctuations with other phase lengths and sporadic fluctuation [ 4].
Theoretically, if a cosine curve is a good model of rhythmic IOP variation and there is not too much sporadic fluctuation superimposed, cosine analysis still yields valid results, because the peak in the early morning hours can be inferred from the other data.
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The source of stochasticity itself varies and includes both the sporadic fluctuations in local transcription factor abundance and the dynamic nature of chromatin.
However, due to the lacking measurements between midnight and 7 am, the risk of an inaccurate estimate increases disproportionately high if rhythmic variation of IOP deviates from a cosine curve or if large sporadic fluctuations are superimposed.
We extended the original criterion by examining changes in CT values over time following treatment so as to determine whether modest fluctuations presented with sporadic directional swings consistent with 'noise' as opposed to trends in contiguous data points consistent with biological effects on gene expression.
Calf #10902 maintained a high PVL from birth until the end of the study (36 months) and calf #10960 showed PVL fluctuations with a sporadic decrease under the PVL threshold of 0.04 BLV copies/cell at 3 6 months of age.
Wide diurnal temperature fluctuations, sun intensity and sporadic heavy rain showers are the propelling factors for the chemical weathering [8].
In particular, in [ 31] based on analysis of skewed scale-dependent distributions of gene expression level in diverse eukaryotic cell types, a random and sporadic "basal" transcription mechanism (analog of low-temperature fluctuations) for protein-coding genes in eukaryotic cell types was predicted.
We were also the generation comprised of millions of latch key kids, divorced parents, erratic fluctuations in the economy, deadly transmitted diseases, and sporadic wars.
The specific mechanism that leads to the initial fluctuations is not important; it is the temporally sporadic, spatially random cytokine secretion that drives downstream noise.
There was no evidence of an increase in the incidence of all cases of sporadic retinoblastoma during the 30-year period studied, nor was there any significant fluctuation in their incidence with space and time.
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