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They persist as rarities in the genomes of a sporadic array of microorganisms, occupying highly conserved sites in diverse proteins.
Successful FANCD2 staining was performed in 96 of the 129 cases of the VUmc sporadic array block.
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While the majority (95%) of cases of AD are sporadic, complex arrays of environmental and genetic factors have also been linked to the etiology of this disorder.
We report the copy number analysis of 21 sporadic chordomas using array comparative genomic hybridization (CGH).
Detailed assessment of chromosome 22 aberrations in sporadic pheochromocytoma using array-CGH.
Further analysis of SNP array data from sporadic MPNSTs showed a similar pattern of stromal loss.
The results presented here, together with information derived from our previous studies [20], [21], are suggestive of a mechanism where podosomes proliferate and transform from individual dynamic structures, that can nucleate sporadic adhesions, to 2-dimensional arrays ("clusters"); from these much more highly dynamic rings are formed, which eventually stabilize.
Sporadic versus Hereditary MTC autophagy gene array results.
Lastly, when comparing clinical sporadic MTC tumors with hereditary cases, array studies revealed an almost universal elevation in autophagy-related genes in SMTC.
Our study is to our knowledge the first array-CGH study of sporadic pheochromocytoma.
The previously demonstrated correlation of RAD21 with survival was also confirmed in the cohort of Buffa et al. of sporadic cancers assessed with gene-expression arrays and in our cohort of familial breast cancers.
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