Sentence examples for sporadic alterations from inspiring English sources

Strains carrying trf4Δ displayed sporadic alterations in copy number.

Finally, the very frequent activation of Ras and PKA pathways, as well as sporadic alterations in TGFβ and Wnt signaling pathways suggest, for the first time, that targeted therapies may have important benefits for these patients, which are currently primarily treated with surgery and chemotherapy.

All mutant animals had sporadic, mild alterations in the vascular structures compared with control animals (Supplementary Material, Fig. S1Ef h, red arrowheads), but we could not detect an earlier onset of vascular malformation in dKO that would be comparable to Tgfbr2-cKO mice.

Unlike sporadic cancers, TP53 alterations occur early in IBD-related carcinogenesis, while APC dysregulation emerges mainly in the most advanced stages of the oncogenic cascade.

Aside from a small subset of patients (∼5%) with inherited genetic alterations, sporadic breast cancer accounts for the majority of all breast cancers and limited knowledge is available about the underlying process of carcinogenesis.

In sporadic cancers, p16 alterations and deletions are more broadly distributed, being found in many types of cancer.

In the overlap disease of sporadic Alzheimer's, alterations in mitochondrial morphology, distribution, and function appear to influence synaptic function [ 51].

Sporadic lesser additions and alterations were made for many years thereafter under other rulers and architects.

Overall, BRCA1 tumors had a higher frequency of copy number alterations than sporadic breast cancers.

In 103 sporadic colorectal cancers no alterations were found in the K-ras, APC or hMLH1 genes.

Using array CGH, we demonstrate recurrent CNAs corresponding to gross chromosomal and/or subchromosomal alterations in sporadic LPTAs.