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Histological autoimmune sialitis, that is spontaneously observed in NOD mice, was also worsened in anti-GITR-treated animals.
PFA is independent of gonadotropins [ 3], occurs prior to puberty, and is spontaneously observed when an ovary is transplanted or cultured in vitro [ 4].
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However, in [ 28], the signal to differentiate is external, and cells therefore cannot differentiate spontaneously as observed.
"It is a bit disturbing that a big firm with worldwide fame did not take far-reaching measures more spontaneously and promptly," observed Luc Van den Bossche, the Belgian health minister.
In some cases BRONJ is observed spontaneously, with some anatomic sites carrying a higher risk.
Within one day, we observed spontaneously pulsating cardiomyocytes.
We observed spontaneously migrating Dictyostelium cells in both a vegetative state (round cell shape and slow motion) and starved one (elongated cell shape and fast motion).
For many years it was arguable if an animal model can be of use in preeclampsia studies, as it was a human disease that was not observed spontaneously in other species.
Assuming that the summed influences of an SSRI and of a 5-HT4 agonishoulduld result in a massive elevation and diffusion of extracellular 5-HT within the DRN, this property could account for the 50% reduction of spontaneously firing cells, observed in both combined treatment groups (Table 1).
The types and incidence of neoplasms that occurred frequently in each group of both sexes were similar to those observed spontaneously in B6C3F1 mice.
In an attempt to repeat the generation of CiPSCs, we unexpectedly observed spontaneously contracting cells or cell clusters resembling cardiomyocytes (Supplementary information, Figure S1A and Movie S1).
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