The data suggest that tissue-engineered bone can lead to the ossification of the alveolar cleft and allow for physiologic spontaneous tooth eruption.
Dentin dysplasia type I (DD-I) is a rare autosomal dominant hereditary disorder which seriously affects the root development of teeth, causing spontaneous tooth loss (in teenagers).
This is the first case report in the literature to show the spontaneous development of teeth in a human reconstructed mandible, contributing evidence toward the functional matrix theory of mandibular growth and ectodermal origin of teeth.
Although a few patients reported a history of oral bleeding associated with dental extractions and/or shedding of deciduous teeth, spontaneous oral bleeding was not reported.
Therefore, the most important finding of this research was that OMFSs and orthodontists are not able to make a reliable prognosis for lower third molar eruption using a panoramic radiograph, when these teeth have spontaneous eruption.
Dental practice and Orthodontics are facing, daily, on the muscular forces exerted by tongue, lips, cheeks, masseter, temporalis anterior etc. during spontaneous saliva swallowing on teeth and on neck muscles.
The erosive OLP can cause spontaneous pain during eating and tooth-brushing.
In extractions, jaw bone remodeling is depressed, leading to the spontaneous breakdown of the wound after the tooth is removed.
We believe that refractory period may be present/relative in milder disease and may become absent with severe disease (saw tooth pattern or very frequent spontaneous attacks) [4, 5].
In addition, teeth can be lost prematurely through spontaneous exfoliation related to a lack of root formation [ 12, 13].
