Our main finding is that variations of some spatial parameters (degree of demixing of the genes, spatial range of the mRNA and proteins) can have dramatic effects on the system dynamics, switching it from the spontaneous oscillatory regime to a stationary regime where each species fluctuates around constant values.
However, many versions of spontaneous alternation test regimes – regarding apparatus and procedure – have been described in the literature, some with alternation rates as high as 93% [e.g. [ 16]].
From a purely theoretical standpoint [ 5- 7], repression-based transcriptional regulation loops (i.e. ring networks), are generically expected to exhibit bistability with hysteresis (even numbers of genes) or a regime of spontaneous periodic oscillations (odd numbers of genes).
Our simulations suggest that variations of spatial parameters – namely the degree of demixing of the positions of the gene or the spatial range of the mRNA and proteins (i.e. the typical distance they travel before degradation) – have dramatic effects by switching the dynamical regime from spontaneous oscillations to a stationary state where each species fluctuates around a constant value.
The analysis of chemiluminescence images enables the delineation of two propagation regimes, namely spontaneous ignition fronts and deflagrations.
In particular, various regimes of spontaneous rhythmical activity were observed, including small-amplitude oscillations, large-amplitude spikes as well as bursting behavior [16].
In this section, we study how these distinct regimes of spontaneous stochastic dynamics affect tuning and amplification properties of the hair cell model in response to external mechanical stimuli.
For a long time the demonstrators in Syria resembled the Shia uprising against Saddam in 1991: a spontaneous, uncoordinated rebellion against the regime.
We found a high sensitivity and frequency selectivity for the regime of regular spontaneous oscillations.
An open question is what training regime (instructed or spontaneous) suits a given athlete best.
Males from the male biased (high conflict, M-regime) regime evolved higher spontaneous locomotor activity and courtship frequency.
