Sentence examples for spontaneous gene from inspiring English sources

Another possibility is that chemicals in the environment cause spontaneous gene alterations, called "de novo" mutations because they arise anew rather than being inherited.

For example, it relies on consistent expression of the XFP, i.e. absence of spontaneous gene silencing.

The spontaneous gene expression of these Smads declined after 72 hours of culture, with Smad4, and to a lesser extent Smad3, still exhibiting higher mRNA levels in HBR-treated than in unexposed cells (Figure 1B, 1C).

Alternative mechanisms of demonstrating partial immunity include spontaneous gene reversion in early lymphoid progenitors [ 52, 59, 60, 74].

The etiology of GWC in this 5 month old male baby could possibly be attributed to spontaneous gene mutation.

The rate of spontaneous gene conversion is generally ∼10−6 events/cell/generation and 10 20% of events are associated with COs (Haber and Hearn 1985).

82 In these regions, spontaneous COL7A1 gene correction, or "revertant mosaicism", is observed on gene analysis, a phenomenon that has been discovered in several inherited skin disorders, including the other type of EB. 83 Cell therapy using revertant keratinocytes is ideal because these cells do not need gene correction.

Although no accurate estimate for the frequency with which [PSI+] is lost has yet been reported, it is certainly lower than 2×10−4 [39] and is probably nearer the frequency for spontaneous nuclear gene mutations i.e. ∼10−6 [40].

Spontaneous, somatic gene mutations such as in the HPRT locus increase exponentially with age in human kidney epithelia [ 71].

In this study, we examined spontaneous mitotic gene conversion in a diploid strain in which conversion events could be measured without selecting against long conversion tracts.

GABA-A receptor impairment has been demonstrated in ataxic mice of the rolling mouse Nagoya and tottering mouse strains due to spontaneous CACNA1A gene mutations.