Exact(4)
Interestingly, HEC-TM cells show spontaneous escape from OIS.
Interestingly, HEC-TM cells displayed spontaneous escape from senescence after oncogenic stress and OIS induction.
We next examined whether LOX activity inhibition by BAPN might prevent the spontaneous escape from senescence observed 45 days after birth.
As increasing LOX activity favors senescence escape, we next investigated whether this spontaneous escape might be inhibited by inhibiting any endogenous LOX activity due to LOX, LOXL1, and/or LOXL2 (Supplementary Figure 1).
Similar(56)
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This approach is expected to establish a significant barrier against spontaneous viral escape from inhibition, since individual viral mutations are less likely to compensate for the loss of an essential host cofactor than to prevent high-affinity binding of a conventional, pathogen-directed antiviral.
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It has long been described that spontaneous mutants escaping cell death arise from SI strains [ 16].
Unfortunately, in 34 of those, depression of spontaneous activity escaped detection in the AC-EEG due to an artefact produced by the automatic drift correction of the BrainAmp amplifier.
We generated two collections of spontaneous mutants allowing escape from het-R het-V or het-C het-E incompatibility, the different steps of the process being presented figure 1 and in Materials and Methods.
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