The hub-and-spoke hypothesis suggests that coherent concepts require both transmodal anterior temporal lobe representations plus these distributed modality-specific sources of information (for discussion of these issues, see: Patterson et al., 2007; Lambon Ralph, 2013).
Modeling of a simplified hub-and-spoke circuit suggests that inhibitory shunting by inactive inputs, combined with lateral facilitation, leads to nonlinear amplification of coincident inputs, a prediction supported by cell ablation and neuroimaging experiments in the nose touch circuit.
This indicates that pairs derived using the matrix model are equally as meaningful (in terms of their functional annotation) as those derived using the spoke model, suggesting that either method provides a valid approach to modelling interactions.
This suggests that the spoke model may be most appropriate for clustering TAP-MS data into complexes.
We analyzed a variety of biological networks and found that the commonly used signature of hierarchical modularity is actually the reflection of spoke-like topology, suggesting a different view of network architecture.
This suggests that flexible models of service delivery (rather than integrated hub-and-spoke models) currently underpin remote outreach provision [ 12].
The Chrysler Building in Midtown Manhattan was an icon to the automobile age when it opened in 1930, with stylized hubcaps and racing cars on setbacks, hood-ornament gargoyles and, over parabolas that suggested the spokes of wheels, a stainless steel spire thrusting skyward like profits.
While the phrase is from Nietzsche's "Thus Spoke Zarathustra," the gallerist Marc Benda suggested the title after reading an interview with the actress Megan Fox.
MRF was applied using the spoke model, using the parameters suggested by Rungsarityotin et al. (2007), i.e. K = 698 and ψ = 3.5.
Our findings suggest the existence of spoke-like topology as opposed to "deterministic hierarchical model".
