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It's a subject well detailed in another upcoming documentary, Al Franken: God Spoke, in which the former Saturday Night Live comedian and political satirist sets up democratic station Air America as a counterpoint to the country's predominantly right-wing talk radio during the 2004 presidential election.
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Arrive at Paris Charles de Gaulle on American Airlines, say, and you will be sucked into a tubular horror of hubs and spokes in which no one but Jacques Tati — or, in a pinch, Fernand Léger — could take pleasure.
A common representation is the so-called spoke model, in which one protein is designated as a hub (or 'bait') and the complex is represented by a set of binary associations, each linking the bait to one of the other proteins ('prey') (25).
Although a rise in O2 evokes an increase in ASH Ca2+, several findings argue against a simple 'hub-to-spoke' model in which ASH and ADL spokes are necessary to relay RMG hub activity outwards to evoke behavioral responses.
What this means in practice is a kind of hub-and-spoke Europe in which diplomacy, bilaterally and in groups, centres on Berlin.
Under deregulation, Mr. Casey swiftly embraced the hub-and-spoke system, in which passengers were funneled from smaller airports to big ones, and then on to their destinations.
That is twice as much as in a conventional airline that runs a hub-and-spoke network, in which aircraft must wait to connect with waves of incoming and outgoing flights.
These researchers say that more powerful microchips and improvements in signal processing -- combined with networking ideas borrowed from the Internet -- may someday eliminate radio's current hub-and-spoke model, in which high-powered transmitters blast signals to dumb receivers.
Instead of the hub-and-spoke system, in which passengers flew in 747s to big hub airports and then took short-haul flights to their final destination, Boeing says that passengers now want the convenience of flying point-to-point and that smaller long-haul planes make it both possible and economical for them to do so.
Hub-and-spoke circuits, in which a central hub neuron is electrically coupled to several input neurons, are an overrepresented motif in the C. elegans nervous system [7] and may represent a conserved functional unit.
Sharp is also converting each market to a hub-and-spoke model, in which only one or two stores will do the heavy lifting — like purchasing the cars at auto auctions and reconditioning them before sale — before shipping the autos to smaller satellite stores.
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