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The study aimed to use the Generalizability Theory to investigate the reliability and precision of the split version of the Global Assessment of Functioning (GAF).
Recently, in 2014, Bačák [26] employed a split version of the PPA for minimizing a sum of convex functions in complete (operatorname{CAT}(0)) spaces.
The clinicians used a split version of the Global Assessment of Functioning Scale.
Symptom severity and function were rated separately with a split version of the Global Assessment of Functioning Scale (GAF) [ 36].
We used a split version of the GAF consisting of two scales ranging from 1-100 for symptom severity and functional impairment, respectively.
We used a split version of the GAF consisting of two scales ranging from 1 to 100 for symptom severity and functional impairment [ 25].
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This same region is the location of bifurcation in the naturally split 5mC methyltransferase M.AquI, the location for circular permutation in M.BssHII, and the location for previously engineered split versions of M.BspRI.
In this study, we combine multiple strategies: a) the use of aptamer probes, short oligonucleotides strands selected in order to present strong selectivity for the small molecule target, b) the sequence engineering of split versions of the aptamer for a sandwich assay and c) the amplification of Surface Plasmon Resonance imaging (SPRi) signal by the use of gold nanoparticles (AuNPs).
Tumours were considered TP53 mutant when (i) more than 15% of the yeast colonies were red and (ii) analysis using the split versions of the test could identify the defect in the 5′ or 3′ part of the gene, confirming the initial determination and (iii) sequence analysis from mutant yeast colonies could identify an unambiguous genetic defect (mutation, deletion, splicing defects…).
General level of symptoms and functioning was assessed with the Global Assessment of Functioning scale (GAF), split version [ 32, 33].
The Global Assessment of Functioning (GAF) split version was used for the overall assessment of symptoms and functioning.
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