Sentence examples for split reads from inspiring English sources
The score increase is greater for evenly split reads than for reads with uneven piece sizes.
To combine the scores for the individual read pieces, they are multiplied, giving a strong bias to evenly split reads.
The mapping produced a SAM formatted file containing mapping coordinates, mapping quality, and information on split reads.
The WTP of this mapping pipeline does not produce de novo split reads that span possible introns.
It requires gene structure definitions in the form of a GTF formatted file to find possible split reads.
Finally, we used split reads as additional line of evidence.
Furthermore, we use a graph-clustering method to identify contigs linked by NEWBLER-split reads that represent divergent alleles, gene duplications, and alternatively spliced transcripts.
For the non-split reads, however, using BLAT would be unnecessarily time-consuming, because their alignment results would usually only contain (if any) a small number of mismatches.
The occurrence of mapped split-reads enables the definition of gene structure and different isoforms.
We then reassembled the new split-reads mappings in combination with the original mappings using Cufflinks.
Cufflinks uses split-reads to lace together exons into a genes and to define isoforms.
