Exact(26)
Therefore, split read realignment without using BWT is necessary to allow reads to be globally mapped.
Paired reads are connected by a green line, with dashed lines representing a split read.
Split read methods (SR) rely on reads that span the break point (Fig. 1).
Thus, we may see a resurgence of pure split read approaches.
The BridgeMapper module creates split read alignments with BLASR that can be used to identify misassemblies.
Thus, the aligned part of a split read may be quite short [e.g. 20 nucleotides (nt)].
Similar(34)
For more on Christina's life post-split, read the full interview on Good Housekeeping.
Pindel was the first split read-based indel detection tool to emerge, and was employed by the 1000 Genomes Project.
By using paired-end mapping and split-read analysis, DELLY identifies deletions, duplications, inversions and translocations in the genomes.
Light blue within reads represent deletions, or a split-read.
Split-read refined calls are annotated by the number of split-reads and the split-read consensus alignment quality against the reference.
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