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The final preovulatory diameter of the dominant follicle was similar in cows from the split dose and single large dose (13.7 ± 0.3 and 13.1 ± 0.5 mm, respectively).
Conclusions: Similar or improved glycemic control was achieved by administering glargine in the morning, evening, or using a split dose without any further increase in severe hypoglycemic episodes.
PPARα WT and KO recipient mice were lethally irradiated with 14 Gy (in a split dose, 4 hours apart) 24 hours before bone marrow transplantation (BMT).
Bowel cleansing regime usually consisted of at least 2 liters macrogole administered as a split dose.
Prospective, single-blind, randomized comparison of split dose PEG-ELS vs. PEG-ELS+simethicone (PEG-S) for outpatient colonoscopy.
Three trials compared the single 40 mg/kg dose with a split dose regimen giving two doses of 20 mg/kg over 24 hours.
Similar(43)
Tiku, A. B. & Kale, R. K. Adaptive response and split-dose effect of radiation on the survival of mice.
Studies of other cleansing agents have suggested that split-dose regimens may further enhance efficacy.
Recent studies using split-dose preparations (SDPs) suggest a significant improvement in the quality of preparation and patient compliance.
Bennett, P. V., Cutter, N. C. & Sutherland, B. M. Split-dose exposures versus dual ion exposure in human cell neoplastic transformation.
Practical guidelines are proposed with regard to the number of subjects per group for SPECT activation studies following the split-dose design.
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